Root Coverage with a New Collagen Matrix and Coronally Advanced Flap: A Case Report

US Food and Drug Administration for regenerative therapy involving teeth and implants, including treatment of dehiscence defects around teeth. Fabricated as a matrix and composed of pure porcine collagen obtained by standardized, controlled manufacturing processes. The collagen was extracted from veterinary-certified pigs and purified to avoid antigenic reactions. The matrix was made of collagen type I and type III without further cross-linking or chemical treatment and sterilized in double blisters by gamma irradiation. CM has two layers and is approximately 2.5 mm thick. The first layer is a compact layer, facing the oral cavity, consisting of a denser collagen that protects the wound but allows tissue adherence for favorable wound healing. This layer has a smooth texture with appropriate properties to accommodate suturing to the host mucosal margins. The second layer is a thicker, porous collagen that encourages tissue integration. This porous surface is placed adjacent to the host tissue to facilitate organization of the blood clot and promote neoangiogenesis [11,12]. Because CM seems to be a promising soft tissue graft substitute, we decided to test in this case report whether its placement under a CAF in a recession defects support root coverage.